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Product Name
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Alpha 2 HS Glycoprotein antibody
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See all Alpha 2 HS Glycoprotein antibodies (6)...
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Product type
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Primary antibodies
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Description
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Sheep polyclonal to Alpha 2 HS Glycoprotein
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Immunogen
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Huma Alpha 2 HS Glycoprotein purified from human serum.
Greater than 95% pure by SDS-PAGE.
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Reacts with
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Hu
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Does not react with
(species key)
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Ms, Rat, Cat, Chk, Cow, Dog, Goat, Gpig, Hrs, Pig, Rb
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Specificity
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This product gives a single arc when tested by IEP and 2D-IEP against human serum.
Identity isconfirmed by double diffusion (Ouchterlony) vs human plasma and a known anti-human alpha 2-HS glycoprotein
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Tested applications
(see key)
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DID, Ie, RID
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Abreviews
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Application notes
(see key)
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Recommended dilutions
RID: 5µL antiserum/cm2 in gel vs 5µL serum from neat - 1/10
Double diffusion: 10µL antiserum vs 2µL serum
IEP: 100µL antiserum vs 5µL serum
The use of 3% PEG 6000 with 1.2%agarose in a suitable buffer (such as TBE or Tris-barbital pH >8.2) is recommended.
Suitability for use in rocket IEP, immunohistochemical procedures, enzyme-linked immunosorbentassays and Western blot has not been assessed but use in such assays should not necessarily beexcluded.
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Cellular localization
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Secreted
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Research areas
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Neuroscience >> Neurology process >> Neurogenesis
Cardiovascular >> Blood >> Serum Proteins
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Relevance
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Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. It promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. It shows affinity for calcium and barium ions.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Sheep
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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IgG fraction
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Storage buffer
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Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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19.000 mg/ml
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Storage instructions
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Store at +4°C.
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