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Products:Cardiovascular >> Blood >> Serum Proteins
Overview
Product name
Anti-Alpha 2 HS Glycoprotein antibody
See all Alpha 2 HS Glycoprotein products (11) ...
Description
Sheep polyclonal to Alpha 2 HS Glycoprotein
Specificity
This product gives a single arc when tested by IEP and 2D-IEP against human serum. Identity isconfirmed by double diffusion (Ouchterlony) vs human plasma and a known anti-human alpha 2-HS glycoprotein
Tested applications
Double Immunodiffusion, RID, Immunoelectrophoresismore details
Cross reactivity
Reacts with
Human
Does not react with
Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
Immunogen
Huma Alpha 2 HS Glycoprotein purified from human serum. Greater than 95% pure by SDS-PAGE.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Polyclonal
Isotype
IgG
Light chain type
unknown
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Cardiovascular >> Blood >> Serum Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab8939 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Double Immunodiffusion
RID
Immunoelectrophoresis
Application notes
RID: 5µL antiserum/cm2 in gel vs 5µL serum from neat - 1/10
Double diffusion: 10µL antiserum vs 2µL serum
IEP: 100µL antiserum vs 5µL serum
The use of 3% PEG 6000 with 1.2%agarose in a suitable buffer (such as TBE or Tris-barbital pH >8.2) is recommended.
Suitability for use in rocket IEP, immunohistochemical procedures, enzyme-linked immunosorbentassays and Western blot has not been assessed but use in such assays should not necessarily beexcluded.
Target
Function
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
Tissue specificity
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
Sequence similarities
Belongs to the fetuin family.
Contains 2 cystatin fetuin-A-type domains.
Post-translational
modifications
Phosphorylation sites are present in the extracelllular medium.
Cellular localization
Secreted.
Target information above from: UniProt accessionP02765
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 59 kDa bone sialic acid-containing protein antibody
- A2HS antibody
- Aa2-066 antibody
see all
Database links
- Entrez Gene: 197 Human
- Omim: 138680 Human
- SwissProt: P02765 Human
- Unigene: 324746 Human
References for Anti-Alpha 2 HS Glycoprotein antibody (ab8939)
This product has been referenced in:
- Kumpalume Pet al. New process for the manufacture of alpha-1 antitrypsin. J Chromatogr A 1148:31-7 (2007).Read more (PubMed: 17350640) »
- Kawakami Tet al. Proteomic analysis of sera from hepatocellular carcinoma patients after radiofrequency ablation treatment. Proteomics 5:4287-95 (2005).Read more (PubMed: 16254924) »
See all 2 publications for this product
Publishing research using ab8939? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"