![Immunocytochemistry/ Immunofluorescence - HSV1 + HSV2 gB antibody [T111] (ab8232) image](#ab8232_1.jpg)
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Products:Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Overview
Product name
Anti-HSV1 + HSV2 gB antibody [T111]
See all HSV1 + HSV2 gB products (2) ...
Description
Mouse monoclonal [T111] to HSV1 + HSV2 gB
Specificity
Recognizes gB antigen of both HSV type 1 and type 2.
Tested applications
ELISA, IF, IPmore details
Immunogen
Extract of HSV-1 infected VERO (green monkey kidney) cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
Purified from ascites using protein A-affinity chromatography.
Clonality
Monoclonal
Clone number
T111
Isotype
IgG2b
Research areas
Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
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Immunocytochemistry/ Immunofluorescence - HSV1 + HSV2 gB antibody [T111] (ab8232)
![Immunocytochemistry/ Immunofluorescence - HSV1 + HSV2 gB antibody [T111] (ab8232) image](/ps/datasheet/Images/8/ab8232/ab8232_1.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab8232 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
IF
IP
Application notes
This antibody was proven to be suitable for detection of HSV in clinical samples.
For immunofluorescence the antibody binds to the surface of infected cells.
Target
Relevance
There are two main types of Herpes Simplex Virus (HSV), 1 and 2. The primary difference between the two types is in where they typically establish latency in the body. HSV1 usually establishes latency in the trigeminal ganglion, a collection of nerve cells near the ear. From there, it tends to recur on the lower lip or face causing cold sores. HSV2 usually resides in the sacral ganglion at the base of the spine. From there, it recurs in the genital area but even this difference is not absolute as in rare cases it can infect any part of the body, including the eyes. Up to 30% of genital herpes are also caused by HSV1. Both HSV1 and 2 are highly contagious through contact.
Cellular localization
Virus envelope
Alternative names
- Envelope glycoprotein B antibody
- GB antibody
- Glycoprotein B antibody
see all
Anti-HSV1 + HSV2 gB antibody [T111] images:
Immunocytochemistry/ Immunofluorescence - HSV1 + HSV2 gB antibody [T111] (ab8232)
ab8232 staining HSV1 + HSV2 gB in HSV trasfected cells by Immunocytochemistry/ Immunofluorescence.
References for Anti-HSV1 + HSV2 gB antibody [T111] (ab8232)
This product has been referenced in:
- Bystricka Met al. Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay. Acta Virol 43:399-402 (1999).Read more (PubMed: 10825932) »
- Bystricka Met al. Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection. Acta Virol 41:5-12 (1997).Read more (PubMed: 9199708) »
See all 3 publications for this product
Publishing research using ab8232? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"