HSV1 + HSV2 gD antibody [12.6] (ab41198)

Product Name 

HSV1 + HSV2 gD antibody [12.6]

Product type 

Primary antibodies

Description 

Mouse monoclonal [12.6] to HSV1 + HSV2 gD

Immunogen 

Tissue / cell preparation: HSV1 + HSV2 gD

Species Reactivity 

Reacts with HSV1 + HSV2.
Not yet tested in other species.

Specificity 

ab41198 recognises HSV1 + HSV2 gD.

Tested applications 
(see key)

ELISA, ICC/IF

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
ELISA: 1/1600.
ICC/IF: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex

Relevance 

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans.
They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. Under a microscope, HSV- 1 and 2 are virtually identical, sharing approximately 50% of their DNA. Both types infect the body's mucosal surfaces, usually the mouth or genitals, and then establish latency in the nervous system. HSV-1 is commonly associated with herpes outbreaks of the face known as cold sores or fever blisters, whereas HSV-2 is more often associated with genital herpes. Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

12.6

Isotype 

IgG1

Purity 

Protein G purified

Storage buffer 

Preservative: None
Constituents: PBS, pH 7.4

Form 

Liquid

Concentration 

19.700 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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