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Read our guarantee »Products:Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Anti-HSV1 + HSV2 gD antibody [2C10]
See all HSV1 + HSV2 gD products (6) ...
Mouse monoclonal [2C10] to HSV1 + HSV2 gD
ICC, WB, ELISAmore details
Herpes Virus
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Phosphate buffered saline
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Protein A purified
Monoclonal
2C10
NS1/1-Ag4-1
IgG2a
kappa
Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Western blot - HSV1 + HSV2 gD antibody [2C10] (ab6507)
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Our Abpromise guarantee covers the use of ab6507 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: 1/102,400 (see reference for Sandwich ELISA).
ICC(IF): 1/3,200 (HSV-2) - 1/25,600 (HSV-1).
WB: 1/10,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans. They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. Under a microscope, HSV- 1 and 2 are virtually identical, sharing approximately 50% of their DNA. Both types infect the body's mucosal surfaces, usually the mouth or genitals, and then establish latency in the nervous system. HSV-1 is commonly associated with herpes outbreaks of the face known as cold sores or fever blisters, whereas HSV-2 is more often associated with genital herpes. Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
Western blot - HSV1 + HSV2 gD antibody [2C10] (ab6507)
![Western blot - HSV1 + HSV2 gD antibody [2C10] (ab6507)](/ps/datasheet/Images/6/ab6507/ab6507.jpg)
Observed band size : 55 kDa (why is the actual band size different from the predicted?)
The WB was completed using the HSV-1 Antigen and the HSV-2 Infected Cell Extract at 10 µg/cm
This product has been referenced in:
See all 4 publications for this product
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![Western blot - HSV1 + HSV2 gD antibody [2C10] (ab6507)](/ps/datasheet/Images/6/ab6507/ab6507.jpg)
Observed band size : 55 kDa (why is the actual band size different from the predicted?)
The WB was completed using the HSV-1 Antigen and the HSV-2 Infected Cell Extract at 10 µg/cm
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