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Products:Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Overview
Product name
Anti-HSV2 gD antibody [A33]
See all HSV2 gD products (2) ...
Description
Mouse monoclonal [A33] to HSV2 gD
Specificity
ab54248 is specific for Herpes Simplex virus 2 glycoprotein D.
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with Herpes Simplex Virus.
Immunogen
Full length native protein (purified) type 2, glycoprotein D (HSV)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
A33
Isotype
IgG1
Research areas
Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54248 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
ELISA
Application notes
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Detects a band of approximately 56-64 kD, corresponding to glycoprotein D, in an HSV (purified) and infected Vero cell lysate immunoblot.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
There are eight members of the herpes virus family that are known to cause human disease, including not only the herpes simplex viruses (HSV1 and HSV2). HSV1 and HSV2 are family Herpesviridae, subfamily Alpha herpes virinae, genus Simplexvirus. Glycoprotein D(gD) binds specifically to the herpesvirus entry mediator receptor (HVEM), thus providing a strong, fixed attachment to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other surface glycoproteins to interact.
Alternative names
- Glycoprotein D precursor antibody
- Herpes Simplex Virus Type 2 Glycoprotein D antibody
- HHV2gp69 antibody
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References for Anti-HSV2 gD antibody [A33] (ab54248)
ab54248 has not yet been referenced specifically in any publications.
Publishing research using ab54248? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"