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Products:Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Overview
Product name
HSV2 gD protein
See all HSV2 gD products (4) ...
Protein description
This protein fragment contains the HSV2 gD immunodominant regions (E.coli derived recombinant protein, amino acids 266-394).
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Purification notes
Sepharose derived purification.
Biological activity
Immunoreactive with sera of HSV infected individuals, excellent antigen for detection of HSV with minimal specificity problems.
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 50% Glycerol, 25mM Tris HCl, 1mM EDTA
Concentration
Concentration information loading...
Research areas
Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Herpes simplex
Applications
Show applications key
Our Abpromise guarantee covers the use of ab43046 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
Protein info
Relevance
There are eight members of the herpes virus family that are known to cause human disease, including not only the herpes simplex viruses (HSV1 and HSV2). HSV1 and HSV2 are family Herpesviridae, subfamily Alpha herpes virinae, genus Simplexvirus. Glycoprotein D(gD) binds specifically to the herpesvirus entry mediator receptor (HVEM), thus providing a strong, fixed attachment to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other surface glycoproteins to interact.
References for HSV2 gD protein (ab43046)
ab43046 has not yet been referenced specifically in any publications.
Publishing research using ab43046? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"