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Product Name 

Haspin antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to Haspin

Immunogen 

Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Haspin.

(Peptide available as ab23532.)

Predicted to react 
(species key)

Hu
(Due to sequence homology)

Tested applications 
(see key)

WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 0.2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 88 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Phosphorylation

Relevance 

Haspin is a member of a distinctive group of protein kinases present in diverse eukaryotes. Haspin phosphorylates histone H3 at T3 in mitotic cells. Haspin is found associated at the centrosomes and spindle during mitosis.


 

Haspin antibody (ab21686)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

83903    (Human)

Omim

    

609240    (Human)

SwissProt

    

Q8TF76    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.100 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Haspin antibody is on this datasheet. But please do contact us if you would like any reassurance!



References for Haspin antibody (ab21686)

Specific publication references   This product has been used in: (two most recent references)

Markaki Y et al. Phosphorylation of histone H3 at Thr3 is part of a combinatorial pattern that marks and configures mitotic chromatin. J Cell Sci 122:2809-19 (2009). WB; Human, Mouse. PubMed: 19622635

Dai J et al. Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion. J Cell Sci 122:4168-76 (2009). WB; Human. PubMed: 19910498
If you publish research using ab21686 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to Haspin

 

Haspin antibody - more information

Customer reviews (feedback) regarding Haspin antibody

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Price and availability of products related to Haspin antibody

 

Haspin antibody - related products:

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Lysates

 

Immunizing Peptide for Haspin antibody

ab23532

  

Haspin peptide

 

Compatible Secondaries for Haspin antibody

ab6564

  

Cy5 ® antibody

ab6717

  

FITC antibody

ab6720

  

Biotin antibody

ab6721

  

HRP antibody

ab6722

  

Alkaline Phosphatase antibody

ab6793

  

Texas Red ® antibody

ab7007

  

Phycoerythrin antibody

ab7019

  

Agarose antibody

ab27234

  

10nm Gold antibody

ab27235

  

5nm Gold antibody

ab27236

  

15nm Gold antibody

ab27237

  

20nm Gold antibody

ab27238

  

30nm Gold antibody

ab27239

  

10nm Gold antibody

ab27240

  

5nm Gold antibody

ab31193

  

Duck polyclonal to Rabbit IgG

ab60314

  

Chromeo™ 488 antibody

ab60315

  

Chromeo™ 494 antibody

ab60317

  

Chromeo™ 546 antibody

ab60319

  

Chromeo™ 642 antibody

 

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