Overview
Product nameHepatitis B Virus Core Antigen proteinSee all Hepatitis B Virus Core Antigen proteins and peptides ...
Protein descriptionRecombinant fragment, AAs 1-144 of HBV core antigen HBcAg, MW 14 kDa. Deleted DNA binding domain. Fully competent for self-assembly. Cloned from HBV 320 genome.(ayw subtype).
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Biological activityReacts strongly with human HBV positive serum.
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 50% Glycerol, 75mM Sodium chloride, 7.5mM PBS, pH 7.2
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab49014
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| WB |
WB: Use at an assay dependent dilution. Predicted molecular weight: 14 kDa. |
| ELISA |
ELISA: Use at an assay dependent dilution. |
Protein info
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Alternative names
CCapsid proteinCore and e antigen
Core antigenCore proteinHBcHBcAgHBVgp4Hepatitis B Virus core antigenp21.5precore/core protein
see all
RelevanceHepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection.
The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
Cellular localizationCapsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
References for Hepatitis B Virus Core Antigen protein (ab49014)
ab49014
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
