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Hepatitis C Virus genotype 3a NS5 protein (ab68626)

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Overview

  • Product nameHepatitis C Virus genotype 3a NS5 proteinSee all Hepatitis C Virus genotype 3a NS5 proteins and peptides ...
  • Protein descriptionRecombinant full length protein containing the Hepatitis C Virus genotype 3a NS5 immunodominant regions.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab68626 was purified by a proprietary chromatographic technique.
  • Biological activityab68626 is immunoreactive with sera of HCV-infected individuals.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab68626 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent dilution.
    ELISA ELISA: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        HCV NS5Hepatitis C virus NS5Non structural protein 5A
        Non structural protein 5BNS5Ap56p68
      see all
  • RelevanceHCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008). NS5B RNA-dependant RNA polymerase is responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication.

    • References for Hepatitis C Virus genotype 3a NS5 protein (ab68626)

    ab68626 has not yet been referenced specifically in any publications.

    Publishing research using ab68626 ? Please let us know so that we can cite the reference in this datasheet

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    Inquiry: can with a count of 13000 of hepititus c 3a virus be treated just with pills

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"