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Western blot - Hephaestin antibody (ab56729)
Western blot - Hephaestin antibody (ab56729)
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Product Name 

Hephaestin antibody

 

See all Hephaestin antibodies (2)...

Product type 

Primary antibodies

Description 

Mouse monoclonal to Hephaestin

Immunogen 

Recombinant fragment, corresponding to amino acids 315-425 of Human Hephaestin

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Membrane. Single-pass type I membrane protein.

Research areas 

Signal Transduction >> Metabolism >> Vitamins / Minerals

Relevance 

HEPH (Hephaestin) may function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. The protein is implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1. HEPH is detected in breast, colon, bone trabecural cells and fibroblasts. It belongs to the multicopper oxidase family.

 

Alternative names Hephaestin antibody (ab56729)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

9843    (Human)

GeneCard

    

GC0XP065299    (Human)

Omim

    

300167    (Human)

SwissProt

    

Q9BQS7    (Human)

Unigene

    

31720    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG2a

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: None
PBS, pH 7.2

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Hephaestin antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Hephaestin antibody images:

Product image  Western blot - Hephaestin antibody (ab56729)

Western blot - Hephaestin antibody (ab56729)



Predicted band size : 130 kDa


Hephaestin antibody (ab56729) at 1ug/lane + K-562 cell lysate at 25ug/lane.

 
 

Search PubMed (MEDLINE) for references to Hephaestin

 

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