Herpes Simplex Virus 2 (HSV 2) IgG Human ELISA Kit (ab108739)
Overview
- Product nameHerpes Simplex Virus 2 (HSV 2) IgG Human ELISA Kit
- Tests1 x 96 test
- Sample typeSerum, Plasma
- Assay typeIndirect
- Species reactivityReacts with: Human
- Product overview
ab108739 Herpes Simplex Virus 2 (HSV 2) IgG Human ELISA Kit is intended for the qualitative determination of IgG class antibodies against HSV Type 2 in human serum or plasma (citrate). It allows the detection of HSV 2 in the presence of antibodies to HSV 1.
Herpes simplex is an enveloped DNA virus (150-200 nm in diameter) belonging to the alpha-herpesviridae. Based on antigenic, biochemical and biologically differences it can be divided into two serotypes, HSV-1 and HSV-2. Man is the only known natural host and source of the virus. HSV type 1 typically causes oral herpes, while HSV type 2 typically affects the genital area. Most of the time, HSV-1 and HSV-2 are inactive, or “silent”, and cause no symptoms, but some infected people have “outbreaks” of blisters and ulcers.
Recombinant gG2 protein of HSV-2 show diffuse band in SDS electrophoresis corresponding to gG2 which is found at approximately 43 kD. This antigen will allow the detection of HSV 2 infection in the presence of antibodies to HSV 1. This is important as the % of the population with HSV 1 increases throughout life up to >90 % at old age. HSV 2 is generally sexually transmitted. Genital herpes is important to diagnose in pregnancy as shedding virus can lead to congenital infection of the child which is invariably serious.
- Tested applicationsIndirect ELISA more details
Properties
- Storage instructionsStore at +4°C. Please refer to protocols.
-
Components Identifier 1 x 96 tests Cover foil 1 unit HSV Type 2 anti-IgG Conjugate Blue, Black cap 1 x 20ml HSV Type 2 Coated Wells (IgG) 12 x 8 tests HSV Type 2 IgG Cut-off Control Yellow, Green cap 1 x 3ml HSV Type 2 IgG Negative Control Yellow, Blue cap 1 x 2ml HSV Type 2 IgG Positive Control Yellow, Red cap 1 x 2ml IgG Sample Diluent Yellow, White cap 1 x 100ml Stop Solution Red cap 1 x 15ml Strip holder 1 unit TMB Substrate Solution Yellow cap 1 x 15ml Washing Solution (20x conc.) White cap 1 x 50ml - Research Areas
-
Alternative names
- Herpes Simplex Virus 2 (HSV 2) IgG
Applications
Our Abpromise guarantee covers the use of ab108739 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Indirect ELISA | I-ELISA |
Protocols
References for Herpes Simplex Virus 2 (HSV 2) IgG Human ELISA Kit (ab108739)
ab108739 has not yet been referenced specifically in any publications.