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Western blot - Hes1 antibody (ab55265)
Western blot - Hes1 antibody (ab55265)
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Product Name 

Hes1 antibody

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal to Hes1

Immunogen 

Recombinant fragment, corresponding to amino acids 36-143 of Human Hes1

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

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(see key)


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WB
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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 30 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Neuroscience >> Neurology process >> Neurogenesis

Relevance 

Hes1 is a transcriptional repressor of genes that require a bHLH protein for their transcription. It may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 is expressed in developing neuroectodermal and endodermal endocrine tissues, and Hes1 deficient embryos show severe defects in neuronal development, as well as pancreatic hypoplasia.

 

Alternative names Hes1 antibody (ab55265)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

3280    (Human)

Omim

    

139605    (Human)

SwissProt

    

Q14469    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG2b

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: None
PBS, pH 7.2

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Hes1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Hes1 antibody images:

Product image  Western blot - Hes1 antibody (ab55265)

Western blot - Hes1 antibody (ab55265)



Predicted band size : 30 kDa


Hes1 antibody (ab55265) at 1ug/lane + THP-1 cell lysate at 25ug/lane.

 
 

Search PubMed (MEDLINE) for references to Hes1

 

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