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Product Name
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Hes1 antibody
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See all Hes1 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Hes1
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Immunogen
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Synthetic peptide derived from the C-terminal domain of (Mouse) Hes1 protein.
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Reacts with
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Ms
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Predicted to react
(species key)
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Hu, Rat
(Due to sequence homology)
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Specificity
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This antibody reacts specifically with mouse 30 kDa Hes1 protein.
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use at an assay dependent dilution.
WB: 1/200 - 1/2000. Predicted molecular weight: 30 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Neuroscience >> Neurology process >> Neurogenesis
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Relevance
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Hes1 is a transcriptional repressor of genes that require a bHLH protein for their transcription. It may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 is expressed in developing neuroectodermal and endodermal endocrine tissues, and Hes1 deficient embryos show severe defects in neuronal development, as well as pancreatic hypoplasia.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Hes1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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References for Hes1 antibody (ab71559)
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This product has been used in:
Karbowniczek M et al. The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development. J Clin Invest 120:93-102 (2010). WB. PubMed: 20038815
If you publish research using ab71559 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to Hes1
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Hes1 antibody - more information
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Customer reviews (feedback) regarding Hes1 antibody |
Customer FAQs regarding Hes1 antibody |
Protocols for Hes1 antibody |
Price and availability of products related to Hes1 antibody |
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Hes1 antibody - related products:
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Hes1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about Hes1 antibody |
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