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Overview

Product name

Hex peptide

Protein description

Synthetic peptide derived from within residues 200 to the C-terminus of Human Hex.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab34222 - Hex antibody.

Protein length

271 amino acids

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Applications

Application notes

This peptide can be used with studies using ab34222.

Protein info

Function

Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.

Tissue specificity

Liver and promyelocytic leukemia cell line HL60.

Sequence similarities

Contains 1 homeobox DNA-binding domain.

Developmental stage

Expressed during hematopoiesis.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ03014 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for Hex peptide (ab28465)

This product has been referenced in:

See 1 publication for this product

Publishing research using ab28465? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"