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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Overview
Product name
Anti-Hey L antibody
See all Hey L products (4) ...
Description
Rabbit polyclonal to Hey L
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow, Dog
Immunogen
A region within synthetic peptide: MKRPKEPSGS DGESDGPIDV GQEGQLSQMA RPLSTPSSSQ MQARKKRRGI, corresponding to N terminal amino acids 1-50 of Human Hey L
MKRPKEPSGS DGESDGPIDV GQEGQLSQMA RPLSTPSSSQ MQARKKRRGI I
Positive control
Foetal muscle lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Transcription Factors
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
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Western blot - Hey L antibody (ab26138)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab26138 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1.0 µg/mlPredicted molecular weight: 35 kDa.
ELISA
ELISA: 1/312500ELISA: 1/312500
Target
Relevance
HEYL belongs to hairy-related bHLH transcription factor family. This 328 amino acid protein contains the basic helix-loop-helix and orange domains conserved in HEY proteins, but it lacks the YRPW motif found in HEY1 and HEY2. HEYL shares 78% amino acid identity with the mouse protein, with most divergence in the C terminal domain. Northern blot analysis of mouse tissues detected a 3.3 kb Heyl transcript in most tissues, with a second, larger Heyl transcript also present in ovary. HEY genes are candidates for several human or mouse disease loci.
Cellular localization
Nuclear
Alternative names
- Hairy related transcription factor 3 antibody
- Hairy enhancer of split related with YRPW motif like antibody
- Hairy-related transcription factor 3 antibody
see all
Database links
- Entrez Gene: 538609 Cow
- Entrez Gene: 26508 Human
- Entrez Gene: 56198 Mouse
- NCBI: NP_055386.1 Human
- Omim: 609034 Human
- SwissProt: Q2NL18 Cow
- SwissProt: Q58CQ8 Cow
- SwissProt: Q5TG99 Human
see all
Anti-Hey L antibody images:
Western blot - Hey L antibody (ab26138)
Anti-Hey L antibody (ab26138) at 1.25 µg/ml + Foetal muscle lysate
Secondary
HRP conjugated anti-Rabbit IgG
Predicted band size : 35 kDa
References for Anti-Hey L antibody (ab26138)
This product has been referenced in:
- Morrow Det al. Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A. Arterioscler Thromb Vasc Biol 29:1112-8 (2009).Read more (PubMed: 19407245) »
See 1 publication for this product
Publishing research using ab26138? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"