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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Overview
Product name
Anti-Hey L antibody
See all Hey L products (4) ...
Description
Rabbit polyclonal to Hey L
Tested applications
IHC-Fr, WBmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Predicted to work with
Horse, Cow, Dog
Immunogen
Synthetic peptide: STPSSSQ MQARKKH, corresponding to amino acids 34-47 of Human Hey L
STPSSSQ MQARKKH
Properties
Form
Lyophilised:
To reconstitute the antibody, centrifuge the antibody vial at moderate speed (5,000 rpm) for 5 minutes to pellet the precipitated antibody product. Carefully remove the ammonium sulfate/PBS buffer solution and discard. It is not necessary to remove all of the ammonium sulfate/PBS solution: Do not let the protein pellet dry, as severe loss of antibody reactivity can occur.
Resuspend the antibody pellet in a suitable biological buffer such as PBS or TBS (pH 7.3-7.5) to a final concentration of 1.0 mg/mL.
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Constituents: 50% Ammonium sulphate, PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Transcription Factors
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Applications
Show applications key
Our Abpromise guarantee covers the use of ab78048 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
IHC-Fr: 1/200 - 1/1000.IHC-Fr: 1/200 - 1/1000.
WB: 1/200 - 1/1000.Predicted molecular weight: 35 kDa.
Target
Relevance
HEYL belongs to hairy-related bHLH transcription factor family. This 328 amino acid protein contains the basic helix-loop-helix and orange domains conserved in HEY proteins, but it lacks the YRPW motif found in HEY1 and HEY2. HEYL shares 78% amino acid identity with the mouse protein, with most divergence in the C terminal domain. Northern blot analysis of mouse tissues detected a 3.3 kb Heyl transcript in most tissues, with a second, larger Heyl transcript also present in ovary. HEY genes are candidates for several human or mouse disease loci.
Cellular localization
Nuclear
Alternative names
- Hairy related transcription factor 3 antibody
- Hairy enhancer of split related with YRPW motif like antibody
- Hairy/enhancer of split related with YRPW motif like antibody
see all
Database links
- Entrez Gene: 538609 Cow
- Entrez Gene: 26508 Human
- Entrez Gene: 56198 Mouse
- NCBI: NP_055386.1 Human
- Omim: 609034 Human
- SwissProt: Q2NL18 Cow
- SwissProt: Q58CQ8 Cow
- SwissProt: Q5TG99 Human
see all
References for Anti-Hey L antibody (ab78048)
ab78048 has not yet been referenced specifically in any publications.
Publishing research using ab78048? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"