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Product Name 

Hey L antibody

 

See all Hey L antibodies (5)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to Hey L

Immunogen 

Synthetic peptide: STPSSSQ MQARKKH, corresponding to amino acids 34-47 of Human Hey L
BLAST 'STPSSSQ MQARKKH' with BLAST the sequence with ExPASy or BLAST the sequence with NCBI

Reacts with 

Hu, Ms, Rat

Predicted to react 
(species key)

Cow, Dog, Hrs
(Due to sequence homology)

Tested applications 
(see key)

IHC-Fr, WB


Abreviews 

Customer reviews
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Application notes 
(see key)

Recommended dilutions
IHC-Fr: 1/200 - 1/1000.
WB: 1/200 - 1/1000. Predicted molecular weight: 35 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH

Relevance 

HEYL belongs to hairy-related bHLH transcription factor family.
This 328 amino acid protein contains the basic helix-loop-helix and orange domains conserved in HEY proteins, but it lacks the YRPW motif found in HEY1 and HEY2. HEYL shares 78% amino acid identity with the mouse protein, with most divergence in the C terminal domain. Northern blot analysis of mouse tissues detected a 3.3 kb Heyl transcript in most tissues, with a second, larger Heyl transcript also present in ovary.
HEY genes are candidates for several human or mouse disease loci.

 

Hey L antibody (ab78048)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

538609    (Cow)
26508    (Human)
56198    (Mouse)

NCBI

    

NP_055386.1    (Human)

Omim

    

609034    (Human)

SwissProt

    

Q2NL18    (Cow)
Q58CQ8    (Cow)
Q9NQ87    (Human)
Q5TG99    (Human)
Q9QXW8    (Mouse)
Q9DBX7    (Mouse)
Q9JJV6    (Mouse)

Unigene

    

472566    (Human)
103615    (Mouse)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: None
Constituents: 50% saturated ammonium sulphate, 1% BSA, PBS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Hey L antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

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