Hey L protein (T7 Tag) (ab40502)

Product Name 

Hey L protein (T7 Tag)

Product type 

Proteins and Peptides

Peptide 

Recombinant full length protein (Human) fused to T7-Tag at the N-terminal end.

Tested applications 
(see key)

SDS-PAGE

Application notes 
(see key)

Recommended dilutions
SDS-PAGE: Use at an assay dependent dilution.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH

Relevance 

HEYL belongs to hairy-related bHLH transcription factor family.
This 328 amino acid protein contains the basic helix-loop-helix and orange domains conserved in HEY proteins, but it lacks the YRPW motif found in HEY1 and HEY2. HEYL shares 78% amino acid identity with the mouse protein, with most divergence in the C terminal domain. Northern blot analysis of mouse tissues detected a 3.3 kb Heyl transcript in most tissues, with a second, larger Heyl transcript also present in ovary.
HEY genes are candidates for several human or mouse disease loci.

Purity 

>95% by SDS-PAGE

Storage buffer 

Preservative: 0.002% Sodium Azide
Constituents: 10mM Tris, 0.1% Triton X-100, 10mM DTT, pH 8.0

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.200 mg/ml

Storage instructions 

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

Expression system 

E. coli

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