Anti-Histidine decarboxylase antibody (ab37291)
Key features and details
- Rabbit polyclonal to Histidine decarboxylase
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-Histidine decarboxylase antibody
See all Histidine decarboxylase primary antibodies -
Description
Rabbit polyclonal to Histidine decarboxylase -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide corresponding to Human Histidine decarboxylase. synthetic peptide around aa 22
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General notes
This product is manufactured by BioVision, an Abcam company and was previously called 3691 HDC Antibody.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 1% BSA, 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab37291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).
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Notes |
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WB
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa). |
Target
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Pathway
Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1. -
Sequence similarities
Belongs to the group II decarboxylase family. - Information by UniProt
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Database links
- Entrez Gene: 24443 Rat
- SwissProt: P16453 Rat
- Unigene: 48653 Rat
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Alternative names
- DCHS_HUMAN antibody
- EC 4.1.1.22 antibody
- HDC antibody
- Histidine decarboxylase antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (14)
ab37291 has been referenced in 14 publications.
- Neumann J et al. Histamine can be Formed and Degraded in the Human and Mouse Heart. Front Pharmacol 12:582916 (2021). PubMed: 34045955
- Li H et al. Histamine deficiency facilitates coronary microthrombosis after myocardial infarction by increasing neutrophil-platelet interactions. J Cell Mol Med 24:3504-3520 (2020). PubMed: 32064748
- Pal S et al. Histamine-mediated autocrine signaling in mesenteric perilymphatic mast cells. Am J Physiol Regul Integr Comp Physiol 318:R590-R604 (2020). PubMed: 31913658
- Davies S et al. Impact of moderate prenatal alcohol exposure on histaminergic neurons, histidine decarboxylase levels and histamine H2 receptors in adult rat offspring. Alcohol 76:47-57 (2019). PubMed: 30557779
- Ocana JA et al. Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms. J Immunol 200:4004-4011 (2018). PubMed: 29695417