Anti-Hsc70 antibody [1D9] (ab90349)
- Product nameAnti-Hsc70 antibody [1D9]See all Hsc70 primary antibodies ...
- DescriptionMouse monoclonal [1D9] to Hsc70
- Tested applicationsWB, IP more details
- Species reactivityReacts with: Arabidopsis thaliana, Tobacco, Potato, Corn, Orange
Predicted to work with: Plants
Recombinant spinach Hsc70 protein
- Positive control
- Apple, Carrot and Spinach plant tissue
- Storage instructionsShipped at 4°C. Store at -20ºC.
- Storage bufferPreservative: 0.09% Sodium Azide
Constituents: 50% Glycerol, PBS
- Concentration information loading...
- PurityProtein G purified
- Purification notesab90349 was purified by Protein G Affinity
- Clonality Monoclonal
- Clone number1D9
- Light chain typekappa
- Research Areas
Our Abpromise guarantee covers the use of ab90349 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: 1/1000. Predicted molecular weight: 78 kDa.|
|IP||IP: Use at an assay dependent dilution.|
- FunctionActs as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
- Tissue specificityUbiquitous.
- Sequence similaritiesBelongs to the heat shock protein 70 family.
- DomainThe N-terminal 1-386 residues constitute the ATPase domain, while residues 387-646 form the peptide-binding domain.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Cellular localizationCytoplasm. Melanosome. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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Anti-Hsc70 antibody [1D9] images
All lanes : Anti-Hsc70 antibody [1D9] (ab90349) at 1/1000 dilution
Lane 1 : Apple
Lane 2 : Carrot
Lane 3 : Spinach
Predicted band size : 78 kDa
References for Anti-Hsc70 antibody [1D9] (ab90349)
ab90349 has not yet been referenced specifically in any publications.