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Full length native protein (purified) (Bovine brain).
Heat shock proteins are produced by prokaryotic and eukaryotic cells, and are among the most conserved molecules in phylogeny. Eukaryotic cells contain an HSP70 multigene that differ in their intracellular location and regulation. Members of the HSP70 family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes, as well as in the immune response. HSP72 was found to increase dramatically in the brains of Alzheimer’s disease patients, and was localized exclusively in neuritic plaques and neurofibrillary tangles. HSP70 concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed.
Our Abpromise guarantee covers the use of ab6535 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC||Use at an assay dependent concentration.|
|Electron Microscopy||Use at an assay dependent dilution.|
|ICC/IF||Use at an assay dependent dilution.|
|IHC-Fr||Use at an assay dependent dilution.|
|Indirect ELISA||Use at an assay dependent dilution.|
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