Overview

  • Product nameAnti-Hsp70 antibody
    See all Hsp70 primary antibodies
  • Description
    Rabbit polyclonal to Hsp70
  • Tested applicationsWB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Sheep, Hamster, Cow, Dog, Human, Pig, Monkey
  • Immunogen

    Synthetic peptide (Human)

  • Positive control
    • Heat shocked HeLa or Vero cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa).
IP 1/100.

Target

  • FunctionIn cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • Tissue specificityHSPA1B is testis-specific.
  • Sequence similaritiesBelongs to the heat shock protein 70 family.
  • Cellular localizationCytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • Database links
  • Alternative names
    • DAQB 147D11.1 001 antibody
    • DnaK type molecular chaperone HSP70 1 antibody
    • Epididymis secretory protein Li 103 antibody
    • FLJ54303 antibody
    • FLJ54370 antibody
    • FLJ54392 antibody
    • FLJ54408 antibody
    • FLJ75127 antibody
    • Heat shock 70 kDa protein 1 antibody
    • Heat shock 70 kDa protein 1/2 antibody
    • Heat shock 70 kDa protein 1A/1B antibody
    • Heat shock 70kDa protein 1A antibody
    • Heat shock 70kDa protein 1B antibody
    • Heat shock induced protein antibody
    • Heat shock protein 70 antibody
    • HEL S 103 antibody
    • HSP70 1 antibody
    • HSP70 1B antibody
    • HSP70 2 antibody
    • HSP70-1/HSP70-2 antibody
    • HSP70-1A antibody
    • HSP70.1 antibody
    • HSP70.1/HSP70.2 antibody
    • HSP70I antibody
    • HSP71_HUMAN antibody
    • HSP72 antibody
    • HSPA1 antibody
    • HSPA1A antibody
    • HSPA1B antibody
    • XXbac BCX40G17.3 001 antibody
    see all

Anti-Hsp70 antibody images

  • All lanes : Anti-Hsp70 antibody (ab69413) at 1/1000 dilution

    Lane 1 : Hsp70 recombinant human protein
    Lane 2 : Hsc70 recombinant bovine protein
    Lane 3 : Cell lysates prepared from heat shock treated Hela cells
    Lane 4 : Cell lysates prepared from heat shock treated PC-12 cells
    Lane 5 : Cell lysates prepared from heat shock treated Vero cells
    Lane 6 : Cell lysates prepared from heat shock treated CHO-K1 cells


    Predicted band size : 70 kDa

References for Anti-Hsp70 antibody (ab69413)

ab69413 has not yet been referenced specifically in any publications.

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