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Product Name 

Human Milk Fat Globule 1 antibody [1.10.F3]

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal [1.10.F3] to Human Milk Fat Globule 1

Immunogen 

Delipidated human milk fat globule membrane.

Reacts with 
(species key)

Hu

Tested applications 
(see key)

IHC-Fr, IHC-P


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-Fr: 1/50 - 1/100.
IHC-P: 1/50 - 1/100.


Is unsuitable for WB.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Normal breast tissue.

Cellular localization 

Cell Membrane and Secreted

Research areas 

Developmental Biology >> Reproduction >> Fertilisation
Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein
Microbiology >> Interspecies Interaction >> Host Virus Interaction

Relevance 

Human Milk Fat Globule 1 (MFG1) is a membrane protein present on normal human breast epithelial cells and cell lines derived from breast carcinomas. Human MFG1 is also localised on the surface of the human milk fat globule. HMFG1 is a differentiation marker and specific breast epithelial marker in normal and neoplastic mammary development. MFG1 Binds specifically to rotavirus and inhibits its replication.

 

Alternative names Human Milk Fat Globule 1 antibody [1.10.F3] (ab49489)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

4240    (Human)

GeneCard

    

GC15M087243    (Human)

Omim

    

602281    (Human)

SwissProt

    

Q08431    (Human)

Unigene

    

3745    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

1.10.F3

Myeloma 

P3-NS1/1-Ag4-1

Isotype 

IgG1

Purity 

Tissue culture supernatant

Storage buffer 

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Human Milk Fat Globule 1 antibody [1.10.F3] is on this datasheet. But please do contact us if you would like any reassurance!



References for Human Milk Fat Globule 1 antibody [1.10.F3] (ab49489)

Specific publication references   This product has been used in:

Tanaka A et al. Expression of Histo-Blood Group A Type 1, 2 and 3 Antigens in Normal Skin and Extramammary Paget's Disease. Acta Histochem Cytochem 41:165-71 (2008). IHC-P; Human. PubMed: 19180201

If you publish research using ab49489 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to Human Milk Fat Globule 1

 

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Breast (human) normal tissue slides

 

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