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Anti-Human Milk Fat Globule 1 antibody [MFG-06] (ab2537)

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Overview

Product name

Anti-Human Milk Fat Globule 1 antibody [MFG-06]
See all Human Milk Fat Globule 1 products (6) ...

Description

Mouse monoclonal [MFG-06] to Human Milk Fat Globule 1

Specificity

Reacts with 40-45 kDa glycoprotein in human milk fat globule membrane preparation.

Tested applications

IHC-P, WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Tissue / cell preparation (Human). Milk fat globule membrane preparation.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4

Concentration

Concentration information loading...

Purity

>95% by SDS-PAGE

Purification notes

Purified from culture supernatant using protein A-affinity chromatography.

Clonality

Monoclonal

Clone number

MFG-06

Isotype

IgG1

Research areas

Developmental Biology >> Reproduction >> Fertilisation
Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein
Microbiology >> Interspecies Interaction >> Host Virus Interaction

Applications

Show applications key

Our Abpromise guarantee covers the use of ab2537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • IHC-P

     

  • WB

     

Application notes

IHC-P: Use at an assay dependant concentration. Strongly positive on human epithelia-based structures.
WB: Use at an assay dependant concentration.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Human Milk Fat Globule 1 (MFG1) is a membrane protein present on normal human breast epithelial cells and cell lines derived from breast carcinomas. Human MFG1 is also localised on the surface of the human milk fat globule. HMFG1 is a differentiation marker and specific breast epithelial marker in normal and neoplastic mammary development. MFG1 Binds specifically to rotavirus and inhibits its replication.

Cellular localization

Cell Membrane and Secreted

Alternative names

  • BA46 antibody
  • Breast epithelial antigen BA46 antibody
  • Contains Medin antibody
  • HMFG antibody
  • Lactadherin [Precursor] antibody
  • Lactadherin antibody
  • Medin antibody
  • MFG E8 antibody
  • MFGE8 antibody
  • MFGM antibody
  • Milk fat globule EGF factor 8 antibody
  • Milk fat globule EGF factor 8 protein antibody
  • O acetyl disialoganglioside synthase antibody
  • OAcGD3S antibody
  • SED1 antibody
see all

Database links

References for Anti-Human Milk Fat Globule 1 antibody [MFG-06] (ab2537)

This product has been referenced in:

  • Bártková Jet al. Differentiation patterns of testicular germ-cell tumours as revealed by a panel of monoclonal antibodies. Tumour Biol 8:45-56 (1987).Read more (PubMed: 2440095) »

See 1 publication for this product

Publishing research using ab2537? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"