Overview
- Product nameAnti-Human Serum Albumin antibodySee all Human Serum Albumin primary antibodies ...
- DescriptionGoat polyclonal to Human Serum Albumin
- SpecificityBy immunoelectrophoresis, the antiserum reacts specifically with human albumin. No antibody was detected against other serum proteins.
- Tested applicationsImmunoelectrophoresis, Double Immunodiffusion more details
- Species reactivityReacts with: Human
- Immunogen
Albumin (Human).
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2 -
Concentration information loading... - PurityImmunogen affinity purified
- Purification notesThe antiserum was fractionated and passed over DEAE to yield an IgG fraction.
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab19179 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Immunoelectrophoresis | |
| Double Immunodiffusion |
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionSerum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
- Tissue specificityPlasma.
- Involvement in diseaseDefects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
- Sequence similaritiesBelongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. - Post-translational
modificationsKenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. - Cellular localizationSecreted.
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Database links
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
Target information above from: UniProt accession
P02768
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- ALB antibodyALBU_HUMAN antibodyAlbumin (32 AA) antibody
- Albumin (AA 34) antibodyAlbumin antibodyAnalbuminemia antibodyBisalbuminemia antibodyCell growth inhibiting protein 42 antibodyDKFZp779N1935 antibodyDysalbuminemic hyperthyroxinemia antibodyGrowth inhibiting protein 20 antibodyHSA antibodyHyperthyroxinemia dysalbuminemic antibodyPRO0883 antibodyPRO0903 antibodyPRO1341 antibodyPRO2044 antibodyPRO2619 antibodySerum albumin antibody
see all
References for Anti-Human Serum Albumin antibody (ab19179)
ab19179 has not yet been referenced specifically in any publications.