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Products:Neuroscience >> Neurotransmission >> Secretory Vesicles >> Other
Overview
Product name
Anti-ICA1 antibody
See all ICA1 products (3) ...
Description
Mouse monoclonal to ICA1
Tested applications
Cross reactivity
Reacts with
Recombinant Fragment
Predicted to work with
Human
Immunogen
Recombinant fragment, corresponding to amino acids 1-111 of Human ICA1
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Immunology >> Immune System Diseases >> Autoimmune
Neuroscience >> Neurotransmission >> Secretory Vesicles >> Other
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Western blot - ICA1 antibody (ab55253)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55253 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
May play a role in neurotransmitter secretion.
Tissue specificity
Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
Sequence similarities
Contains 1 AH domain.
Cellular localization
Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle > secretory vesicle membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Target information above from: UniProt accessionQ05084
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 69 kDa islet cell autoantigen antibody
- Diabetes mellitus type I autoantigen antibody
- ICA 1 antibody
see all
Database links
- Entrez Gene: 3382 Human
- Omim: 147625 Human
- SwissProt: Q05084 Human
- Unigene: 487561 Human
Anti-ICA1 antibody images:
Western blot - ICA1 antibody (ab55253)
Western blot against tagged recombinant protein immunogen using ab55253 ICA1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
References for Anti-ICA1 antibody (ab55253)
ab55253 has not yet been referenced specifically in any publications.
Publishing research using ab55253? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"