Anti-ICAD antibody [2262C2a] (ab71967)

Overview

• Product nameAnti-ICAD antibody [2262C2a]See all ICAD primary antibodies ...
• Description
  Mouse monoclonal [2262C2a] to ICAD
• Tested applicationsWB, Dot Blot more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant fragment of human ICAD

• Positive controlRecombinant human ICAD.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.05% Sodium Azide
  Constituents: 1% BSA, PBS (8.0mM Sodium phosphate, 3.0mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate, pH 7.4)
• Concentration information loading...
• PurityProtein G purified
• Purification notesab71967 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
• Clonality Monoclonal
• Clone number2262C2a
• IsotypeIgG1
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Apoptosis

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Apoptosis
  • Nuclear

  • Cell Biology
  • Apoptosis
  • Nucleus
  • DNAses

Applications

Target

• FunctionInhibitor of the caspase-activated DNase (DFF40).
• Sequence similaritiesContains 1 CIDE-N domain.
• Post-translational
  modificationsCaspase-3 cleaves DFF45 at 2 sites to generate an active factor.
  Phosphorylated upon DNA damage, probably by ATM or ATR.
• Cellular localizationCytoplasm.

Target information above from: UniProt accession O00273 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 1676 Human
  • Omim: 601882 Human
  • SwissProt: O00273 Human
  • Unigene: 484782 Human

• Alternative names
  A330085O09Rik antibodyCaspase activated deoxyribonuclease inhibitor short form antibodyDFF 1 antibody

  DFF 45 antibodyDFF alpha antibodyDFF-45 antibodyDFF1 antibodyDFF35 antibodyDFF45 antibodyDFFA antibodyDffa DNA fragmentation factor, alpha subunit antibodyDFFA_HUMAN antibodyDNA fragmentation factor 45 kDa subunit antibodyDNA Fragmentation Factor Alpha Subunit antibodyDNA fragmentation factor subunit alpha antibodyDNA fragmentation factor, 45 kD, alpha subunit antibodyDNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1 antibodyDNA fragmentation factor, 45kDa, alpha polypeptide antibodyDNA fragmentation factor, alpha subunit antibodyDNAation factor 45 kDa subunit antibodyH13 antibodyICAD antibodyICAD L antibodyICAD S antibodyInhibitor of CAD antibodyInhibitor of Caspase Activated DNase antibodyMGC143066 antibodyOTTHUMP00000001903 antibodyOTTHUMP00000001904 antibodyRP23 121D17.3 antibody

  see all

Anti-ICAD antibody [2262C2a] images

• 

  Western blot - ICAD antibody [2262C2a] (ab71967)
  Anti-ICAD antibody [2262C2a] (ab71967) + immunising recombinant protein
  
  Predicted band size : 37 kDa
  Observed band size : 35 kDa (why is the actual band size different from the predicted?)