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Product Name 

ICAM2 antibody [3C4] (Biotin)

 

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Product type 

Primary antibodies

Description 

Rat monoclonal [3C4] to ICAM2 (Biotin)

Immunogen 

Tissue / cell preparation (Mouse) - COS cells transfected with ICAM2 cDNA.

Reacts with 
(species key)

Ms

Specificity 

ab25262 recognises Mouse ICAM-2 (CD102).

Tested applications 
(see key)

BL, Flow Cyt, IHC-Fr, IP


Abreviews 

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Application notes 
(see key)

Recommended dilutions
BL: Use at an assay dependent dilution.
Flow Cyt: Use 1µg for 106 cells.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Type I membrane protein

Research areas 

Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Immunology >> Cell Type Markers >> CD >> Adhesion

Relevance 

ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

This antibody blocks the interaction between ICAM-2 and LFA-1.

 

ICAM2 antibody [3C4] (Biotin) (ab25262)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

15896    (Mouse)

SwissProt

    

P35330    (Mouse)

Raised in 

Rat

Clonality 

Monoclonal

Clone number 

3C4

Isotype 

IgG2a

Light chain type 

kappa

Purity 

IgG fraction

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Conjugation 

Biotin

Concentration 

0.500 mg/ml

Storage instructions 

Store at +4°C in the dark.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ICAM2 antibody [3C4] (Biotin) is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to ICAM2

 

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ICAM2 antibody [3C4] (Biotin) - related products:

 

Compatible Secondaries for ICAM2 antibody [3C4] (Biotin)

ab6565

  

Cy5 ® antibody

ab6730

  

FITC antibody

ab6733

  

Biotin antibody

ab6734

  

HRP antibody

ab6843

  

Texas Red ® antibody

ab6846

  

Alkaline Phosphatase antibody

ab7010

  

Phycoerythrin antibody

ab7020

  

Agarose antibody

 

Other ICAM2 Antibodies

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ICAM2 antibody [3C4] (Biotin) - other tools:

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