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Product Name
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ICAM2 antibody [3C4] (Biotin)
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See all ICAM2 antibodies (15)...
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Product type
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Primary antibodies
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Description
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Rat monoclonal [3C4] to ICAM2 (Biotin)
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Immunogen
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Tissue / cell preparation (Mouse) - COS cells transfected with ICAM2 cDNA.
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Reacts with
(species key)
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Ms
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Specificity
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ab25262 recognises Mouse ICAM-2 (CD102).
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Tested applications
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BL, Flow Cyt, IHC-Fr, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions BL: Use at an assay dependent dilution. Flow Cyt: Use 1µg for 106 cells. IHC-Fr: Use at an assay dependent dilution. IP: Use at an assay dependent dilution.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Type I membrane protein
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Research areas
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Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage Immunology >> Cell Type Markers >> CD >> Adhesion
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Relevance
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ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
This antibody blocks the interaction between ICAM-2 and LFA-1.
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ICAM2 antibody [3C4] (Biotin) (ab25262)
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 15896 (Mouse)
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Raised in
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Rat
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Clonality
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Monoclonal
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Clone number
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3C4
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.1% Sodium Azide Constituents: PBS Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Form
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Liquid
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Conjugation
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Biotin
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C in the dark.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ICAM2 antibody [3C4] (Biotin) is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to ICAM2
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ICAM2 antibody [3C4] (Biotin) - more information
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