|
|
|
|
Flow Cytometry / FACS - ICAM3 antibody [B-R1] (ab47031)
![Flow Cytometry / FACS - ICAM3 antibody [B-R1] (ab47031)](/ps/datasheet/images/47031.gif)
(enlarge)
|
|
|
|
|
Product Name
|
ICAM3 antibody [B-R1] - Azide free
|
| |
See all ICAM3 antibodies (13)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal [B-R1] to ICAM3 - Azide free
|
|
Immunogen
|
Tissue / cell preparation of U266 cell line (Human)
|
|
Reacts with
(species key)
|
Hu
|
|
Tested applications
(see key)
|
Flow Cyt, IP
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
Flow Cyt: Use at 1ug/test.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Cell Membrane; Type I membrane protein.
|
|
Research areas
|
Immunology >> Cell Type Markers >> CD >> Adhesion
Signal Transduction >> Adapters >> Transmembrane
Signal Transduction >> Protein Phosphorylation >> pSer / pThr
|
|
Relevance
|
All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA1 protein. ICAM3 is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Upon stimulation by a physiological stimulus it becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Clone number
|
B-R1
|
|
Myeloma
|
x63-Ag8.653
|
|
Isotype
|
IgG1
|
|
Purity
|
Ion Exchange Chromatography
|
|
Storage buffer
|
Preservative: None
Constituents: PBS
|
|
Purification notes
|
Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ICAM3 antibody [B-R1] - Azide free is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
|
See below for ICAM3 antibody [B-R1] - Azide free images, references, products related to ab47031 and other tools.
|
| |
ICAM3 antibody [B-R1] - Azide free images:
|
 Flow Cytometry / FACS - ICAM3 antibody [B-R1] (ab47031)
A typical staining pattern with the B-R1 monoclonal antibody of lymphocytes
|
| |
| |
|
Search PubMed (MEDLINE) for references to ICAM3
|
| |
ICAM3 antibody [B-R1] - Azide free - more information
|
Customer reviews (feedback) regarding ICAM3 antibody [B-R1] - Azide free |
Customer FAQs regarding ICAM3 antibody [B-R1] - Azide free |
Protocols for ICAM3 antibody [B-R1] - Azide free |
Price and availability of products related to ICAM3 antibody [B-R1] - Azide free |
| |
ICAM3 antibody [B-R1] - Azide free - related products:
|
|
|
| |
ICAM3 antibody [B-R1] - Azide free - other tools:
|
Contact Abcam with a Technical Enquiry about ICAM3 antibody [B-R1] - Azide free |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
![Flow Cytometry / FACS - ICAM3 antibody [B-R1] (ab47031)](/index.html?datasheet=47031#47031.gif)
