Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Protein Phosphorylation >> pSer / pThr
Overview
Product name
Anti-ICAM3 antibody
See all ICAM3 products (12) ...
Description
Mouse monoclonal to ICAM3
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 30-548 of Human ICAM3
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2b
Light chain type
kappa
Research areas
Immunology >> Cell Type Markers >> CD >> Adhesion
Signal Transduction >> Adapters >> Transmembrane
Signal Transduction >> Protein Phosphorylation >> pSer / pThr
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55254 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.
Sequence similarities
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Post-translational
modifications
Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues.
N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Cellular localization
Membrane.
Target information above from: UniProt accessionP32942
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CD50 antibody
- CDW 50 antibody
- CDw50 antibody
see all
Database links
- Entrez Gene: 3385 Human
- Omim: 146631 Human
- SwissProt: P32942 Human
- Unigene: 353214 Human
- Unigene: 654563 Human
Anti-ICAM3 antibody images:
IHC-P - ICAM3 antibody (ab55254)
ICAM3 antibody (ab55254) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human stomach carcinoma tissue.
Western blot - ICAM3 antibody (ab55254)
ICAM3 antibody (ab55254) at 1ug/lane + HL-60 cell lysate at 25ug/lane.
References for Anti-ICAM3 antibody (ab55254)
ab55254 has not yet been referenced specifically in any publications.
Publishing research using ab55254? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"