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Products:Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins
Overview
Product name
Anti-ICAM5 antibody
See all ICAM5 products (2) ...
Description
Goat polyclonal to ICAM5
Tested applications
ELISA, IHC-Pmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat
Immunogen
Synthetic peptide: C-ESPAEGEVFAIQ, corresponding to C terminal amino acids 909-920 of Human ICAM5
C-ESPAEGEV FAIQ
Positive control
Lysates of Human brain - frontal cortex and hippocampus. Mouse brain lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Tags & Cell Markers >> Cell Type Markers >> Neuroscience Markers >> Neuronal
Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ICAM5 antibody (ab53561)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab53561 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/32000ELISA: 1/32000
IHC-P: Use a concentration of 2 - 4 µg/ml.Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Target
Relevance
ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Cellular localization
Membrane; single-pass type I membrane protein
Alternative names
- ICAM5 precursor antibody
- Intercellular adhesion molecule 5 antibody
- Intercellular adhesion molecule 5 precursor antibody
see all
Database links
- Entrez Gene: 7087 Human
- Entrez Gene: 15898 Mouse
- Entrez Gene: 313785 Rat
- Omim: 601852 Human
- SwissProt: Q9UMF0 Human
- SwissProt: Q60625 Mouse
- Unigene: 465862 Human
- Unigene: 59765 Rat
Anti-ICAM5 antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ICAM5 antibody (ab53561)
ab53561 at 2.5µg/ml staining human brain (cerebral cortex) tissue sections by immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections). The tissue sections subjected to antigen retrieval by steam with citrate buffer. The AP-staining staining procedure was used for detection.
References for Anti-ICAM5 antibody (ab53561)
ab53561 has not yet been referenced specifically in any publications.
Publishing research using ab53561? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"