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Products:Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins
Overview
Product name
Anti-ICAM5 antibody
See all ICAM5 products (2) ...
Description
Rabbit polyclonal to ICAM5
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow, Dog, Chimpanzee
Immunogen
Synthetic peptide corresponding to a region within the N terminal amino acids 72-121 (RRNGTQRGLR WLARQLVDIR EPETQPVCFF RCARRTLQAR GLIRTFQRPD) of human ICAM5 (NP_003250).
RRNGTQRGLR WLARQLVDIR EPETQPVCFF RCARRTLQAR GLIRTFQRPD
Positive control
293T cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
ab85191 is purified by peptide affinity chromatography method.
Clonality
Polyclonal
Isotype
IgG
Research areas
Tags & Cell Markers >> Cell Type Markers >> Neuroscience Markers >> Neuronal
Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins
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Western blot - ICAM5 antibody (ab85191)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab85191 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 µg/mlPredicted molecular weight: 97 kDa.
Target
Relevance
ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Cellular localization
Membrane; single-pass type I membrane protein
Alternative names
- ICAM5 precursor antibody
- Intercellular adhesion molecule 5 antibody
- Intercellular adhesion molecule 5 precursor antibody
see all
Database links
- Entrez Gene: 7087 Human
- Entrez Gene: 15898 Mouse
- Entrez Gene: 313785 Rat
- Omim: 601852 Human
- SwissProt: Q9UMF0 Human
- SwissProt: Q60625 Mouse
- Unigene: 465862 Human
- Unigene: 59765 Rat
Anti-ICAM5 antibody images:
Western blot - ICAM5 antibody (ab85191)
Anti-ICAM5 antibody (ab85191) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 97 kDa
Observed band size : 97 kDa
Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.
6-18% gel
References for Anti-ICAM5 antibody (ab85191)
ab85191 has not yet been referenced specifically in any publications.
Publishing research using ab85191? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"