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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Overview
Product name
Anti-ID2 antibody
See all ID2 products (7) ...
Description
Rabbit polyclonal to ID2
Tested applications
IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
A synthetic peptide from C-terminal of human ID2 protein
Positive control
Breast carcinoma.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 10mM PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Stem Cells >> Signaling Pathways >> TGF beta >> Nuclear
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ID2 antibody (ab52093)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab52093 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
IHC-P: 1/50 for 30 min at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.
Tissue specificity
Highly expressed in early fetal tissues, including those of the central nervous system.
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Developmental stage
Found in most early fetal tissues but not in the corresponding mature tissues.
Cellular localization
Cytoplasm. Nucleus.
Target information above from: UniProt accessionQ02363
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- bHLHb26 antibody
- Cell growth inhibiting gene 8 antibody
- Class B basic helix-loop-helix protein 26 antibody
see all
Database links
- Entrez Gene: 3398 Human
- Omim: 600386 Human
- SwissProt: Q02363 Human
- Unigene: 180919 Human
Anti-ID2 antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ID2 antibody (ab52093)
Staining of ID2 in human breast carcinoma by immunohistochemistry, using ab52093 (1/50). (Formalin fixed, Paraffin embedded section).
References for Anti-ID2 antibody (ab52093)
ab52093 has not yet been referenced specifically in any publications.
Publishing research using ab52093? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"