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Anti-ID2 antibody (ab87189)

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Overview

Product name

Anti-ID2 antibody
See all ID2 products (7) ...

Description

Rabbit polyclonal to ID2

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Cow, Pig

Immunogen

Synthetic peptide corresponding to a region within internal sequence amino acids 85-134 (IVSLHHQRPG QNQASRTPLT TLNTDISILS LQASEFPSEL MSNDSKALCG) of human ID2 (NP_002157).

IVSLHHQRPG QNQASRTPLT TLNTDISILS LQASEFPSEL MSNDSKALCG

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Human fetal thymus nuclear lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

Purified by peptide affinity chromatography method.

Clonality

Polyclonal

Isotype

IgG

Research areas

Stem Cells >> Signaling Pathways >> TGF beta >> Nuclear
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH

  • Western blot - ID2 antibody (ab87189)Western blot - ID2 antibody (ab87189) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab87189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.

Tissue specificity

Highly expressed in early fetal tissues, including those of the central nervous system.

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain.

Developmental stage

Found in most early fetal tissues but not in the corresponding mature tissues.

Cellular localization

Cytoplasm. Nucleus.

Target information above from: UniProt accessionQ02363 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • bHLHb26 antibody
  • Cell growth inhibiting gene 8 antibody
  • Class B basic helix-loop-helix protein 26 antibody
  • DNA binding protein inhibitor ID 2 antibody
  • DNA-binding protein inhibitor ID-2 antibody
  • GIG8 antibody
  • Helix loop helix protein ID2 antibody
  • ID2 antibody
  • ID2_HUMAN antibody
  • ID2A antibody
  • ID2H antibody
  • Inhibitor of differentiation 2 antibody
  • Inhibitor of DNA binding 2 antibody
  • Inhibitor of DNA binding 2, dominant negative helix loop helix protein antibody
  • MGC26389 antibody
see all

Database links

see all

Anti-ID2 antibody images:

  Western blot - ID2 antibody (ab87189)

Western blot - ID2 antibody (ab87189)

Anti-ID2 antibody (ab87189) at 1 µg/ml + human fetal thymus lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 15 kDa
Observed band size : 15 kDa

References for Anti-ID2 antibody (ab87189)

ab87189 has not yet been referenced specifically in any publications.

Publishing research using ab87189? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"