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Products:Cell Biology >> Apoptosis >> Nucleus >> Other
Overview
Product name
Anti-ID3 antibody [2B11]
See all ID3 products (8) ...
Description
Mouse monoclonal [2B11] to ID3
Tested applications
IP, WB, ICC/IFmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Recombinant full length protein (Human) ID3 expressed in E. coli.
Properties
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
2B11
Isotype
IgG1
Research areas
Cancer >> Signal transduction >> Other
Stem Cells >> Signaling Pathways >> TGF beta >> Nuclear
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Immunology >> Adaptive Immunity >> B Cells >> Non-CD
Cell Biology >> Apoptosis >> Nucleus >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab36501 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 16 kDa.
ICC/IF: Use at an assay dependent dilution.
Target
Function
ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.
Tissue specificity
Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain.
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ02535
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 1R21 antibody
- bHLHb25 antibody
- Class B basic helix-loop-helix protein 25 antibody
see all
Database links
- Entrez Gene: 3399 Human
- Entrez Gene: 15903 Mouse
- Omim: 600277 Human
- SwissProt: Q02535 Human
- SwissProt: P41133 Mouse
- Unigene: 76884 Human
- Unigene: 110 Mouse
References for Anti-ID3 antibody [2B11] (ab36501)
ab36501 has not yet been referenced specifically in any publications.
Publishing research using ab36501? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"