Overview

  • Product nameAnti-IDH3B antibodySee all IDH3B primary antibodies ...
  • Description
    Rabbit polyclonal to IDH3B
  • Tested applicationsWB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 90-378 of Human IDH3B (BC001960).

  • Positive control
    • Human placenta, fetal heart and Jurkat cell lysates; Human fetal skeletal muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab112544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 42 kDa).
ELISA 1/20000 - 1/80000.
IHC-P 1/100 - 1/500.

Target

  • Involvement in diseaseDefects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similaritiesBelongs to the isocitrate and isopropylmalate dehydrogenases family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ11043 antibody
    • H-IDHB antibody
    • IDH3B antibody
    • IDH3B_HUMAN antibody
    • Isocitrate dehydrogenase [NAD] subunit beta antibody
    • Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial antibody
    • isocitrate dehydrogenase 3, beta subunit antibody
    • Isocitric dehydrogenase antibody
    • Isocitric dehydrogenase subunit beta antibody
    • MGC903 antibody
    • mitochondrial antibody
    • NAD(+)-specific ICDH antibody
    • NAD(+)-specific ICDH subunit beta antibody
    • NAD+-specific isocitrate dehydrogenase b subunit antibody
    • NAD+-specific isocitrate dehydrogenase beta antibody
    • OTTHUMP00000030023 antibody
    • OTTHUMP00000030024 antibody
    • RP46 antibody
    see all

Anti-IDH3B antibody images

  • All lanes : Anti-IDH3B antibody (ab112544) at 1/500 dilution

    Lane 1 : Human fetal heart lysate
    Lane 2 : Human placenta lysate
    Lane 3 : Jurkat cell lysate


    Predicted band size : 42 kDa
  • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human fetal skeletal muscle tissue, using ab112544 at 1/100 dilution. Note cytoplasmic staining.

References for Anti-IDH3B antibody (ab112544)

ab112544 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"