IGF1 Receptor beta subunit protein (Active) (ab80349)
Constituents: 50mM Tris, 1mM DTT, pH 7.5
Our Abpromise guarantee covers the use of ab80349 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Functional Studies||FuncS: Use at an assay dependent dilution. May also be useful for enzyme kinetics, autophosphorylation and phosphorylation of target substrates.|
|SDS-PAGE||SDS-PAGE: Use at an assay dependent dilution.|
- CD221CD221 antigenEC 126.96.36.199
- IGF I receptorIGF-I receptorIGF1RIGF1R_HUMANIGFIRInsulin like growth factor 1 receptor alpha chainInsulin like growth factor 1 receptor beta chainInsulin like growth factor I receptorInsulin-like growth factor 1 receptor beta chainInsulin-like growth factor I receptorJTK13MGC142170MGC142172MGC18216Soluble IGF1R variant 1Soluble IGF1R variant 2
Contains 3 fibronectin type-III domains.
Contains 1 protein kinase domain.
modificationsThe cytoplasmic domain of the beta subunit is autophosphorylated on tyrosine residues in response to insulin-like growth factor I (IGF I).
Phosphorylation of Tyr-980 is required for IRS1- and SHC1-binding.
References for IGF1 Receptor beta subunit protein (Active) (ab80349)
ab80349 has not yet been referenced specifically in any publications.