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Products:Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Overview
Product name
Anti-IGF1 antibody [1F6-3H10]
See all IGF1 products (13) ...
Description
Mouse monoclonal [1F6-3H10] to IGF1
Specificity
Reacts with hIGF-1 100% Does not cross react with hIGF-2, Insulin (human), EGF (human) or TGF-alpha
Tested applications
WB, Indirect ELISA, IFmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein (Human)
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Ascites
Concentration
Concentration information loading...
Purity
Ascites
Clonality
Monoclonal
Clone number
1F6-3H10
Isotype
IgG1
Light chain type
kappa
Applications
Show applications key
Our Abpromise guarantee covers the use of ab40789 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/5000Detects a band of approximately 17 kDa (predicted molecular weight: 7.5 kDa).(With this antibody, we have found that blocking with 5% goat or donkey serum significantly reduces background as compared to BSA or milk.)
Indirect ELISA
I-ELISA: 1/5000I-ELISA: 1/5000
IF
IF: 1/2000IF: 1/2000
Target
Relevance
Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
Cellular localization
Secreted
Form
There are 2 isoforms produced by alternative splicing. Isoform 1 also known as: IGF-IB; Isoform 2 also known as: IGF-IA.
Alternative names
- IBP1 antibody
- IGF 1 antibody
- IGF I antibody
see all
Database links
- Entrez Gene: 3479 Human
- Omim: 147440 Human
- SwissProt: P05019 Human
- Unigene: 160562 Human
References for Anti-IGF1 antibody [1F6-3H10] (ab40789)
This product has been referenced in:
- Rezaei Bet al. Electrochemical impedimetric immunosensor for insulin like growth factor-1 using specific monoclonal antibody-nanogold modified electrode. Biosens Bioelectron 26:2130-4 (2011).Read more (PubMed: 20933383) »
See 1 publication for this product
Publishing research using ab40789? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"