Anti-IGF1 antibody [RM0099-2F54] (ab86468)

Overview

• Product nameAnti-IGF1 antibody [RM0099-2F54]See all IGF1 primary antibodies ...
• Description
  Hamster monoclonal [RM0099-2F54] to IGF1
• Specificityab86468 detects mouse IGF1 in western blotting
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Mouse
  
• Immunogen

  Mouse recombinant IGF1 protein

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
• Concentration information loading...
• PurityProtein G purified
• Purification notesThe IgG fraction of culture supernatant was purified by protein A/G affinity chromatography and 0.2 µm filtered
• Clonality Monoclonal
• Clone numberRM0099-2F54
• IsotypeIgG2
• Research Areas
  • Developmental Biology
  • Post embryonic development
  • Growth hormones

  • Developmental Biology
  • Post embryonic development
  • Aging

  • Cancer
  • Growth factors
  • Insulin and insulin-like

  • Signal Transduction
  • Growth Factors/Hormones
  • Insulin / Insulin-like

Applications

Target

• FunctionThe insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
• Involvement in diseaseDefects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
• Sequence similaritiesBelongs to the insulin family.
• Cellular localizationSecreted.

Target information above from: UniProt accession P05019 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 16000 Mouse
  • SwissProt: P05017 Mouse
  • Unigene: 268521 Mouse

• Alternative names
  IBP1 antibodyIGF I antibodyIGF IA antibody

  IGF IB antibodyIGF-I antibodyIgf1 antibodyIGF1_HUMAN antibodyIGFI antibodyIGFIA antibodyInsulin like growth factor 1 (somatomedin C) antibodyInsulin like growth factor 1 antibodyInsulin like growth factor IA antibodyInsulin like growth factor IB antibodyInsulin-like growth factor I antibodyMechano growth factor antibodyMGF antibodyOTTHUMP00000195080 antibodyOTTHUMP00000195081 antibodyOTTHUMP00000195082 antibodyOTTHUMP00000195083 antibodyOTTHUMP00000195084 antibodySomatomedin C antibodySomatomedin-C antibody

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