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Product Name 

IGF1 antibody

 

See all IGF1 antibodies (14)...

Product type 

Primary antibodies

Description 

Mouse monoclonal to IGF1

Immunogen 

Recombinant full length protein (Rat).

Reacts with 

Ms, Rat

Does not react with 
(species key)

Hu

Specificity 

As determined by EIA, this antibody shows 100 % reactivity with rat and mouse IGF1. It also shows <0.4 % cross reactivity with rat IGF2, and <0.05 % cross reactivity with human IGF1 or IGF2.

Tested applications 
(see key)

Dot, ELISA, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
Dot: 1/5000.
ELISA: 1/2000.
WB: A dilution of 1/5000 detects 250 ng IGF1. Predicted molecular weight: 17 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Secreted

Research areas 

Developmental Biology >> Post embryonic development >> Growth hormones
Developmental Biology >> Post embryonic development >> Aging
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like

Relevance 

Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.

 

Alternative names IGF1 antibody (ab36532)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

16000    (Mouse)
24482    (Rat)

SwissProt

    

P05017    (Mouse)
P08025    (Rat)

Unigene

    

6282    (Rat)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG2b

Light chain type 

kappa

Purity 

IgG fraction

Storage buffer 

Preservative: None
Constituents: PBS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this IGF1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to IGF1

 

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