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Anti-IGF1 antibody (ab36532)

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Overview

Product name

Anti-IGF1 antibody
See all IGF1 products (13) ...

Description

Mouse monoclonal to IGF1

Specificity

As determined by EIA, this antibody shows 100 % reactivity with rat and mouse IGF1. It also shows <0.4 % cross reactivity with rat IGF2, and <0.05 % cross reactivity with human IGF1 or IGF2.

Tested applications

Dot Blot, WB, ELISAmore details

Cross reactivity

Reacts with

Mouse, Rat

Does not react with

Human

Immunogen

Recombinant full length protein (Rat).

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS

Concentration

Concentration information loading...

Purity

IgG fraction

Clonality

Monoclonal

Isotype

IgG2b

Light chain type

kappa

Research areas

Developmental Biology >> Post embryonic development >> Growth hormones
Developmental Biology >> Post embryonic development >> Aging
Cancer >> Growth factors >> Insulin and insulin-like
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like

Applications

Show applications key

Our Abpromise guarantee covers the use of ab36532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Dot Blot

     

  • WB

     

  • ELISA

     

Application notes

Dot: 1/5000.
ELISA: 1/2000.
WB: A dilution of 1/5000 detects 250 ng IGF1. Predicted molecular weight: 17 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.

Cellular localization

Secreted

Form

There are 2 isoforms produced by alternative splicing. Isoform 1 also known as: IGF-IB; Isoform 2 also known as: IGF-IA.

Alternative names

  • IBP1 antibody
  • IGF 1 antibody
  • IGF I antibody
  • IGF IA antibody
  • IGF IB antibody
  • IGF1 antibody
  • IGFI antibody
  • IGFIA antibody
  • Insulin like growth factor 1 (somatomedin C) antibody
  • Insulin Like Growth Factor 1 antibody
  • Insulin like growth factor IA antibody
  • Insulin like growth factor IB antibody
  • insulin-like growth factor I antibody
  • Mechano growth factor antibody
  • MGF antibody
  • OTTHUMP00000195080 antibody
  • OTTHUMP00000195081 antibody
  • OTTHUMP00000195082 antibody
  • OTTHUMP00000195083 antibody
  • OTTHUMP00000195084 antibody
  • Somatomedia C antibody
  • Somatomedin C antibody
see all

Database links

References for Anti-IGF1 antibody (ab36532)

This product has been referenced in:

  • Hamzeh M & Robaire B Identification of early response genes and pathway activated by androgens in the initial segment and caput regions of the regressed rat epididymis. Endocrinology 151:4504-14 (2010). WB; Rat.Read more (PubMed: 20660069) »

See 1 publication for this product

Publishing research using ab36532? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"