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Product Name
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IGF1 antibody
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See all IGF1 antibodies (14)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to IGF1
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Immunogen
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Synthetic human insulin-like growth factor 1 [Ac60-70] covalently attached onto a carrier protein.
BLAST 'AcDALQFVCGDRG' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Many
(Due to sequence homology)
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Specificity
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Insulin-like growth factor 1 (human) 100%; IGF-2 (human) <0.1%; IGF-2(rat) <0.1%
Does not cross react with Insulin (human), EGF, TGFa
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Tested applications
(see key)
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IHC (PFA fixed)
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Immunohistochemistry (PFA fixed): 1/1000.
With this antibody, we have found that blocking with 5% goat or donkey serum significantly reduces background as compared to BSA or milk.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Developmental Biology >> Post embryonic development >> Growth hormones
Developmental Biology >> Post embryonic development >> Aging
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
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Relevance
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Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks) (add antibacterial agent). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this IGF1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to IGF1
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IGF1 antibody - more information
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Customer reviews (feedback) regarding IGF1 antibody |
Customer FAQs regarding IGF1 antibody |
Protocols for IGF1 antibody |
Price and availability of products related to IGF1 antibody |
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Contact Abcam with a Technical Enquiry about IGF1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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