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Products:Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Overview
Product name
Anti-IGF1 antibody
See all IGF1 products (13) ...
Description
Rabbit polyclonal to IGF1
Specificity
Insulin-like growth factor 1 (human) 100%; IGF-2 (human) <0.1%; IGF-2(rat) <0.1% Does not cross react with Insulin (human), EGF, TGFa
Tested applications
IHC (PFA fixed)more details
Cross reactivity
Reacts with
Human
Predicted to work with
a wide range of other species
Immunogen
Synthetic human insulin-like growth factor 1 [Ac60-70] covalently attached onto a carrier protein.
AcDALQFVCG DRG
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks) (add antibacterial agent). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Applications
Show applications key
Our Abpromise guarantee covers the use of ab40657 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC (PFA fixed)
IHC (PFA fixed): 1/1000IHC (PFA fixed): 1/1000
Target
Relevance
Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
Cellular localization
Secreted
Form
There are 2 isoforms produced by alternative splicing. Isoform 1 also known as: IGF-IB; Isoform 2 also known as: IGF-IA.
Alternative names
- IBP1 antibody
- IGF 1 antibody
- IGF I antibody
see all
Database links
- Entrez Gene: 3479 Human
- Omim: 147440 Human
- SwissProt: P05019 Human
- Unigene: 160562 Human
References for Anti-IGF1 antibody (ab40657)
ab40657 has not yet been referenced specifically in any publications.
Publishing research using ab40657? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"