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Products:Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Overview
Product name
IGF1 protein
See all IGF1 products (13) ...
Protein description
Human IGF-I.
Expression host
E. coli
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Concentration
Concentration information loading...
Additional notes
The biological activity is determined by its ability to stimulate the proliferation of mouse FDC-P1 cells.
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Reconstitute in water.
Sequence notes
Human IGF-I is a 7.6 kDa protein containing 70 amino acid residues: GPETLCG AEL VDALQFVCG D RGFYFNKP TG YGSSSRR APQ TGIVDE CCFR SCDLR RLEMYCAPLK PAKSA
Research areas
Stem Cells >> Stem Cell Cytokines >> Recombinant Human
Developmental Biology >> Post embryonic development >> Growth hormones
Developmental Biology >> Post embryonic development >> Aging
Cancer >> Growth factors >> Insulin and insulin-like
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Applications
Show applications key
Our Abpromise guarantee covers the use of ab9573 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FuncS: Use at an assay dependent dilution.
SDS-PAGE: Use at an assay dependent dilution.
Application notes
This peptide can be used with studies using ab9572.
Protein info
Relevance
Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
Cellular localization
Secreted
References for IGF1 protein (ab9573)
ab9573 has not yet been referenced specifically in any publications.
Publishing research using ab9573? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"