IGF2 protein (Active) (ab9575)
Our Abpromise guarantee covers the use of ab9575 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Functional Studies||FuncS: Use at an assay dependent dilution.|
|SDS-PAGE||SDS-PAGE: Use at an assay dependent dilution.|
- IGF 2IGF IIIGF-IIIGF2IGF2_HUMANIGFIIINSIGFInsulin like Growth Factor 2insulin like growth factor 2 (somatomedin A)Insulin like growth factor IIInsulin like growth factor II precursorInsulin like growth factor type 2Insulin-like Growth Factor 2Insulin-like Growth Factor 2pp9974Preptinputative insulin like growth factor II associated proteinSomatomedin ASomatomedin ASomatomedin-A
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
modificationsO-glycosylated with a core 1 or possibly core 8 glycan.
IGF2 protein (Active) images
References for IGF2 protein (Active) (ab9575)
This product has been referenced in:
- Suvasini R et al. Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2. J Biol Chem 286:25882-90 (2011). Read more (PubMed: 21613208) »