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Anti-IGFBP2 antibody [1.A.16] (ab4243)

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Overview

Product name

Anti-IGFBP2 antibody [1.A.16]
See all IGFBP2 products (7) ...

Description

Mouse monoclonal [1.A.16] to IGFBP2

Specificity

Recognizes human IGFBP 2 on ELISA analysis.

Tested applications

ELISA, WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Yeast derived recombinant protein (Human).

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

0.1M Tris HCl, pH 7.5, 50% glycerol

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

1.A.16

Isotype

IgM

Applications

Show applications key

Our Abpromise guarantee covers the use of ab4243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Sequence similarities

Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.

Domain

The C-terminus is required for IGF-binding and growth inhibition.

Post-translational
modifications

O-glycosylated.

Cellular localization

Secreted.

Target information above from: UniProt accessionP18065 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • BP 2 antibody
  • BP2 antibody
  • IBP 2 antibody
  • IBP-2 antibody
  • IBP2 antibody
  • IBP2_HUMAN antibody
  • IGF binding protein 2 antibody
  • IGF BP53 antibody
  • IGF-binding protein 2 antibody
  • IGFBP 2 antibody
  • IGFBP-2 antibody
  • IGFBP2 antibody
  • IGFBP53 antibody
  • Insulin like growth factor binding protein 2 36kDa antibody
  • Insulin Like Growth Factor Binding Protein 2 antibody
  • Insulin like growth factor-binding protein 2 precursor antibody
  • Insulin-like growth factor-binding protein 2 antibody
see all

References for Anti-IGFBP2 antibody [1.A.16] (ab4243)

This product has been referenced in:

  • Walker Get al. Insulin-like growth factor binding proteins IGFBP3, IGFBP4, and IGFBP5 predict endocrine responsiveness in patients with ovarian cancer. Clin Cancer Res 13:1438-44 (2007).Read more (PubMed: 17332286) »

See 1 publication for this product

Publishing research using ab4243? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"