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Overview

  • Product nameIGFBP4 proteinSee all IGFBP4 proteins and peptides ...
  • Protein descriptionHuman Recombinant full length IGFBP4 derived from Insect cells, 237 amino acids, 25.8 kDa. Swiss ID = P22692.
  • Expression hostBaculovirus infected insect (BTI-TN-5B1-4) cells

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesPurity is greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Storage instructionsAliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • Sequence notesDEAIHCPPCS EEKLARCRPP VGCEELVREP GCGCCATCAL GLGMPCGVYT PRCGSGLRCY PPRGVEKPLH TLMHGQGVCM ELAEIEAIQE SLQPSDKDEG DHPNNSFSPC SAHDRRCLQK HFAKIRDRST SGGKMKVNGA PREDARPVPQ GSCQSELHRA LERLAASQSR THEDLYIIPI PNCDRNGNFH PKQCHPALDG QRGKCWCVDR KTGVKLPGGL EPKGELDCHQ LADSFRE
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab69504 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE
    Functional Studies
  • Application notesBiological Activity : Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.
    SDS-PAGE: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        AI875747BP 4BP4
        Deb2HT29 IGFBPIBP 4IBP-4IBP4IBP4_HUMANIGF binding protein 4IGF-binding protein 4IGF-BP4IGFBP 4IGFBP-4IGFBP4Insulin Like Growth Factor Binding Protein 4Insulin-like growth factor-binding protein 4
      see all
  • FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • Sequence similaritiesContains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P22692 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for IGFBP4 protein (ab69504)

    ab69504 has not yet been referenced specifically in any publications.

    Publishing research using ab69504 ? Please let us know so that we can cite the reference in this datasheet

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    I was wondering if this protein needs to be cleaved in order to be activated or it is active the way it comes Thanks

    Thank you for your inquiry. We can confirm that our ab69504 is a active protein and no further processing is required for this protein. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"