Anti-IGFBP6 antibody [1.A.19] (ab4258)

Overview

• Product nameAnti-IGFBP6 antibody [1.A.19]See all IGFBP6 primary antibodies ...
• Description
  Mouse monoclonal [1.A.19] to IGFBP6
• SpecificityRecognizes human IGFBP 6 on ELISA analysis.
• Tested applicationsELISA more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Human recombinant IGF binding Protein 6 (yeast derived recombinant protein).

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage buffer0.1M Tris HCl, pH 7.5, 50% glycerol
• Concentration information loading...
• PurityProtein G purified
• Clonality Monoclonal
• Clone number1.A.19
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Other

  • Signal Transduction
  • Growth Factors/Hormones
  • Insulin / Insulin-like

Applications

Target

• FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
• Sequence similaritiesContains 1 IGFBP N-terminal domain.
  Contains 1 thyroglobulin type-1 domain.
• Post-translational
  modificationsO-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylated on one site only in the region AA 143-168 in cerebrospinal fluid.
• Cellular localizationSecreted.

Target information above from: UniProt accession P24592 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3489 Human
  • Omim: 146735 Human
  • SwissProt: P24592 Human
  • Unigene: 274313 Human

• Alternative names
  IBP 6 antibodyIBP-6 antibodyIBP6 antibody

  IBP6_HUMAN antibodyIGF binding protein 6 antibodyIGF-binding protein 6 antibodyIGFBP 6 antibodyIGFBP-6 antibodyIGFBP4 antibodyIGFBP6 antibodyInsulin Like Growth Factor Binding Protein 6 antibodyInsulin-like growth factor-binding protein 6 antibody

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