Overview
Product nameIL1 alpha proteinSee all IL1 alpha proteins and peptides ...
Protein descriptionRecombinant fragment, corresponding to amino acids 120-268 of Cow IL1 alpha produced in yeast; 149 amino acids, Predicted MWt 17.1kDa, (Swiss-Prot P08831).
Expression hostYeast
Properties
Purity> 95
% by SDS-PAGE
Purification notesab87390 is purified by Ion-exchange chromatography.
FormLyophilised:Reconstitute with sterile Phosphate-buffered saline containing at least 0.1% carrier protein.
Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Storage instructionsStore at -20°C. Stable for 12 months at -20°C
Storage bufferPreservative: None
Constituents: 10% Trehalose, 1.0X PBS
Concentration information loading...
Sequence notesSNVKYNFMRV IHQECILNDA LNQSIIRDMS GPYLTATTLN NLEEAVKFDM VAYVSEEDSQ LPVTLRISKT QLFVSAQNED EPVLLKEMPE TPKIIKDETN LLFFWEKHGS MDYFKSVAHP KLFIATKQEK LVHMASGPPS ITDFQILEK
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab87390
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
| SDS-PAGE |
SDS-PAGE: Use at an assay dependent dilution. |
Protein info
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Alternative names
Hematopoietin-1IL 1 alphaIL 1AIL-1 alphaIl-1aIL1IL1 ALPHAIL1AIL1A_HUMANIL1F1Interleukin 1 alphaInterleukin-1 alphaInterleukin1 alphaLAFLEMPreinterleukin 1 alphaPro interleukin 1 alpha
see all
FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Sequence similaritiesBelongs to the IL-1 family.
DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
References for IL1 alpha protein (ab87390)
ab87390
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
