Anti-IL1 beta antibody [5C10] (HRP) (ab8321)

Overview

  • Product nameAnti-IL1 beta antibody [5C10] (HRP)
    See all IL1 beta primary antibodies
  • Description
    Mouse monoclonal [5C10] to IL1 beta (HRP)
  • ConjugationHRP
  • SpecificityDoes not inhibit the biological activity of Interleukin-1.
  • Tested applicationsELISA, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant beta human Interleukin-1

Properties

Applications

Our Abpromise guarantee covers the use of ab8321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.

Target

  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • Catabolin antibody
    • H1 antibody
    • Hematopoietin 1 antibody
    • IFN beta inducing factor antibody
    • IL 1 antibody
    • IL 1 beta antibody
    • IL 1B antibody
    • IL-1 beta antibody
    • IL1 BETA antibody
    • IL1B antibody
    • IL1B_HUMAN antibody
    • IL1F2 antibody
    • Interleukin 1 beta antibody
    • Interleukin 1 beta precursor antibody
    • Interleukin-1 beta antibody
    • LAF antibody
    • OAF antibody
    • Osteoclast activating factor antibody
    • OTTHUMP00000162031 antibody
    • Preinterleukin 1 beta antibody
    • Preinterleukin beta antibody
    • Pro interleukin 1 beta antibody
    see all

References for Anti-IL1 beta antibody [5C10] (HRP) (ab8321)

ab8321 has not yet been referenced specifically in any publications.

Product Wall

I have processed your request to receive new vials of ab8319 and ab8321. Your new order numbers are****** and ******. Both antibodies re in stock and should arrive by 10.30am tomorrow morning.

This antibody has not been tested for cross-reactivity in rat, therefore we cannot guarantee results.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"