Overview

  • Product nameAnti-IL1 beta antibody [B-A15]
    See all IL1 beta primary antibodies
  • Description
    Mouse monoclonal [B-A15] to IL1 beta
  • SpecificityThis antibody is specific for both natural (pro and mature) and recombinant IL1 beta.
  • Tested applicationsBlocking, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length IL1 beta protein (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab47193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Blocking
Flow Cyt
  • Application notesBL: Use at an assay dependent dilution. Blocks IL1 beta induced proliferation on D10S murine cell line.
    FACS(intra-cytoplasmic): Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
    • Sequence similaritiesBelongs to the IL-1 family.
    • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
    • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
    • Information by UniProt
    • Database links
    • Alternative names
      • Catabolin antibody
      • H1 antibody
      • IL 1 antibody
      • IL 1 beta antibody
      • IL-1 beta antibody
      • IL1 BETA antibody
      • IL1B antibody
      • IL1B_HUMAN antibody
      • IL1F2 antibody
      • Interleukin 1 beta antibody
      • Interleukin-1 beta antibody
      • OAF antibody
      • OTTHUMP00000162031 antibody
      • Preinterleukin 1 beta antibody
      • Pro interleukin 1 beta antibody
      see all

    References for Anti-IL1 beta antibody [B-A15] (ab47193)

    ab47193 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"