Overview

  • Product nameAnti-IL1 beta antibody (Biotin)
    See all IL1 beta primary antibodies
  • Description
    Rabbit polyclonal to IL1 beta (Biotin)
  • ConjugationBiotin
  • SpecificitySpecific for bovine interleukin-1 beta (IL-1 beta).Recognises both native and recombinant bovine IL-1 beta.
  • Tested applicationsELISAmore details
  • Species reactivity
    Reacts with: Cow

    Does not react with

    Mouse, Rat, Human
  • Immunogen

    Recombinant bovine IL-1 beta.

  • General notes


    Antisera to bovine IL-1 beta were raised by repeated immunisation of rabbits with highly purified antigen. Endotoxin Level: <0.015 EU/ug

Properties

Applications

Our Abpromise guarantee covers the use of ab23778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 1 - 10 µg/ml.

Target

  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • Catabolin antibody
    • H1 antibody
    • Hematopoietin 1 antibody
    • IFN beta inducing factor antibody
    • IL 1 antibody
    • IL 1 beta antibody
    • IL 1B antibody
    • IL-1 beta antibody
    • IL1 BETA antibody
    • IL1B antibody
    • IL1B_HUMAN antibody
    • IL1F2 antibody
    • Interleukin 1 beta antibody
    • Interleukin 1 beta precursor antibody
    • Interleukin-1 beta antibody
    • LAF antibody
    • OAF antibody
    • Osteoclast activating factor antibody
    • OTTHUMP00000162031 antibody
    • Preinterleukin 1 beta antibody
    • Preinterleukin beta antibody
    • Pro interleukin 1 beta antibody
    see all

References for Anti-IL1 beta antibody (Biotin) (ab23778)

This product has been referenced in:
  • Kasimanickam RK  et al. Associations among serum pro- and anti-inflammatory cytokines, metabolic mediators, body condition, and uterine disease in postpartum dairy cows. Reprod Biol Endocrinol 11:103 (2013). ELISA ; Cow . Read more (PubMed: 24209779) »

See 1 Publication for this product

Product Wall

Unfortunately the immunogen is not currently available for purchase.



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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"