Anti-IL1 beta antibody [S1B7] (ab18646)
- Product nameAnti-IL1 beta antibody [S1B7]See all IL1 beta primary antibodies ...
- DescriptionMouse monoclonal [S1B7] to IL1 beta
- Specificityab18646 detects endogenous and recombinant IL1 beta. ab18646 does not show any cross reactivity with recombinant IL1 alpha, recombinant murine IL1 alpha or IL1 beta.
- Tested applicationsELISA more details
- Species reactivityReacts with: Human
Purified recombinant IL1 beta (Human).
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: 0.01M PBS, pH 7.2
- Concentration information loading...
- PurityProtein G purified
- Clonality Monoclonal
- Clone numberS1B7
- Light chain typekappa
- Research Areas
Our Abpromise guarantee covers the use of ab18646 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||ELISA: Use at an assay dependent dilution.|
- FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
- Sequence similaritiesBelongs to the IL-1 family.
- DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
- Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
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References for Anti-IL1 beta antibody [S1B7] (ab18646)
ab18646 has not yet been referenced specifically in any publications.